Pr. Patrick Pale

Université de Strasbourg

 

Laboratory of Organic Synthesis, Institute of Chemistry

Université de Strasbourg

4, rue Blaise Pascal, 67000 Strasbourg

France

Tel/fax: (+33) 3 68 85 15 17

e-mail: ppale(a)unistra.fr


Education:


  1. Doctorat  (PhD)  1982

  2. Chemistry and photochemistry of organometallic Pd complexes

  3. University of Champagne, Reims, France

  4. Doctorat d'État (Habilitation)  1988

  5. Studies of the mechanisms of sigmatro-pic rearrangements. Formation of oxygenated heterocycles

  6. University of Champagne, Reims, France


Position & Experiences:


  1. 1982 associate researcher at the Research Center of I.C.I.-Pharma-France (now Astra-Zeneca), France.

  2. Total and hemisyntheses of penicillins and cephalosporins

  3. 1983 associate researcher at the Université Catholique de Louvain, Louvain-la-Neuve, Belgium.

  4. Pr  L. GHOSEZ  

  5. Synthesis and reactivity of azadienes

  6. 1988-1990 associate researcher at Harvard University,  Cambridge, USA

  7. Pr  G. WHITESIDES  

  8. Enzymatic organic synthesis, carbohydrate chemistry, chemical and enzymatic synthesis of glycosyl nucleotides.

  9. 1984-1994  CNRS fellow (researcher) at the University of Champagne, Reims, France.

  10. Mechanistic studies of rearrangement reactions; Formation of oxygenated heterocycles; Pheromones synthesis; Spiroketal synthesis; Chemical and enzymatic transformations of raw materials from agriculture.

  11. Since 1995Professor at the Université L. Pasteur (now University of Strasbourg), Strasbourg, France.


  13. 2002Invited Professor at the Science University of Tokyo, Japan, 1 month

  14. 2004Invited Professor at the Academia Sinica, Taipeh, Taiwan, 1 month

  15. 2008Invited Professor at the Université de Bamako, Mali and Université de Batna, Algérie

  16. 2009Invited Professor at the University of Hokkaido, Sapporo, Japon, 1 month


Distinction:


  1. 1996-2001 member of the "Institut Universitaire de France"

  2. 2010 Favorskii Lecturer, Russian Academy of Science


Publications:


  1. More than 110 publications (72 since 2000) and 79 invited lectures


Current scientific activities


  1. 1.Total synthesis of bioactive products : oxylipines ; dienediyne antitumor antibiotics ; toxic metabolites produced by Caulerpa taxifolia, the alga invading the Mediterranean Sea, etc

  2. 2.Chemistry for biology : A novel way to block HIV replication ; new MRI reagents ; new agents for the study of the dynamic of genome, etc

  3. 3.New methodologies : Alkynyloxirane chemistry, Organosilver in organic synthesis, Silver & Gold catalysis; Asymmetric synthesis, based on asymmetric catalysis, biocatalysis and carbohydrate templates;

  4. 4.Chemistry in Nanoreactors : Green Chemistry, zeolites as catalysts in organic synthesis