Dr. Christophe Meyer

ESPCI - ParisTech - Paris

 

ESPCI ParisTech

Laboratoire de Chimie Organique

10 rue Vauquelin 75231 Paris Cedex 05 – France

Phone : +33.1.40.79.58.45

E-mail : christophe.meyer(a)espci.fr


Born 30/05/1969


1988–1991 : Engineering Studies in Chemistry

Ecole Nationale Supérieure de Chimie de Paris (ENSCP)


1991–1994 : PhD in Organic Chemistry, Université Pierre et Marie Curie (Paris VI)

Research supervisors: Prof. Jean NORMANT and Dr. Ilan MAREK

Intramolecular carbozincation reactions of alkenes and alkynes


1994-1995 : Research Associate (Military Service)

Ecole Supérieure de Techniques Avanceés, Paris / Dr. Laurent EL KAIM

Development of a new access to iminyl radicals


1995–1996 : Post-Doctoral Researcher (Lavoisier Fellowship)

University of Toronto (Canada) / Prof. Mark LAUTENS

Palladium-catalyzed hydrostannylation of unactivated alkenes and methylenecyclopropanes


Since 1996 : Researcher at the CNRS

Ecole Supérieure de Physique et Chimie Industrielles (ESPCI ParisTech)

Laboratory of Organic Chemistry / Prof. Janine COSSY

CNRS Bronze Medal Award (2000)

Promoted Director of Research (2008)


Research interests


  1. •Development of synthetic methods: ring-closing and ring-rearrangement metathesis reactions, electrophilic ring-opening of cyclopropylcarbinols, reactivity of functionalized ynamides and enamides, [2,3]-Wittig sigmatropic rearrangements, gold- and rhodium-catalyzed ring-opening reactions of cyclopropenes


  1. •Total synthesis of bioactive natural products and analogues: (-)-4a,5-dihydrostreptazolin, zincophorin, mycothiazole, amphidinolide J, cytostatin, palmerolide A, phoslactomycin B


Selected recent publications


  1. •Rhodium-Catalyzed Cycloisomerization Involving Cyclopropenes: Efficient Stereoselective Synthesis of Medium-Sized Heterocyclic Scaffolds: Miege, F.; Meyer, C.; Cossy, J. Angew. Chem. Int. Ed. 2011, 50, doi:10.1002/anie.201101220.

  2. •Copper-Free Sonogashira Coupling of Cyclopropyl Iodides with Terminal Alkynes: De Carné-Carnavalet, B.; Archambeau, A.; Meyer, C.; Cossy, J.; Folléas, B.; Brayer, J.-L.; Demoute, J.-P. Org. Lett. 2011, 13, 956–959.

  3. •Synthesis of 1,2-Amino Alcohols by Sigmatropic Rearrangements of 3-(N-Tosylamino)allylic Alcohol Derivatives: Barbazanges, M.; Meyer, C.; Cossy, J.; Turner, P. Chem. Eur. J. 2011, 17, 4480–4495.

  4. •Synthesis of 3-Oxa and 3-Azabicyclo[4.1.0]heptanes by Gold-Catalyzed Cycloisomerization of Cyclopropenes: Miege, F.; Meyer, C.; Cossy, J. Org. Lett. 2010, 12, 4144–4147.

  5. •Ring-Rearrangement Metathesis of Cyclopropenes. Synthesis of Heterocycles: Miege, F.; Meyer, C.; Cossy, J. Org. Lett. 2010, 12, 248–251.